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"Wat we obtain too cheap, we esteem too lightly". Paine
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Do you want to know how you can save time and get higher profits, make your product competitive and ensure its sale on world market? Well ! But first I invite you to analyze together situation around conditions of problem. The XX century, latest period of history of analytical chemistry, was specially rich in innovations. A great significance had invention of chromatography (M. S. Tswett, 1903) and subsequent development of its varieties.
The analyses of a great number of substances are based on use of chromatographic principles of separation. On this same principle are based separation of isotopes and therefore creation of atomic weapon and atomic power stations.
Six Nobel prizes were won by Carrer in 1932, Kuhn in 1938, Ruzicka in 1939, Martin and Synge in 1952, Sanger in 1958 and 1980 - authors, whose achievements depended to a significant degree on use of chromatographic analysis.
In development of chromatography, a process that goes on up to-day, a definite tendency is traced. After substantial theoretical and technological "gush" it follows to provide equipment with additional parts allowing enlargement of analytical possibilities of chromatograph. On this background it is considered in - time development of Chromabarography - a new basic technology of chromatography.
What does it present itself, what does it give to user and producer of equipment? After all, heart of chromatography is chromatographic column. The theory of gas chromatography, presented by equation of Van Deemter H = A + B/u + Cu shows that for each chromatographic separation there exists an optimal flow rate above and below which column efficiency is reduced.
In practice, linear speed of sample zone moved by carrier gas, is changed continuously and increases as it approaches outlet, which results in a non-effective use of a part of column.
Yet linear speed may be kept constant by programming movement of pressure gradient along column, realizing function pressure - location - time and keeping ∆ p constant at ends of chromatographic column during whole process of analysis.
For first time in world this basic technology was worked out and proposed by me, based on investigation of factors of diffusion and kinetics, and includes meaning "bar-gradient chromatography" or Chromabarography. For its realization an equipment was invented and defended by a Russia patent. As a result a maximum possible efficiency (Hayrapetyan's Effect) of column is obtained at a minimum length, which at same time is optimal as well, as in difference to ordinary column further increase in column length increases analyses time. However these are not only advantages of Chromabarography. On contrary, new interesting possibilities of its modifications are opened which foresee: of combined application of moving gradients of pressure and temperature (Chromabarothermography)
or of moving of pressure gradient along column simultaneously with temperature programming affected equally on all separation column (Chromabarograph with temperature programming). Amongst other advantages of scientific value may be mentioned: The possibility of bar-focusing on each component to solve complex analytical problems on a singular gas chromatographic column, in difference to two or multistage columns.