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Do you want to know how you can save time and get higher profits, make your product competitive and ensure its sale on world market? Well ! But first I invite you to analyze together
situation around
conditions of
problem. The XX century,
latest period of
history of analytical chemistry, was specially rich in innovations. A great significance had
invention of chromatography (M. S. Tswett, 1903) and
subsequent development of its varieties.
The analyses of a great number of substances are based on
use of chromatographic principles of separation. On this same principle are based
separation of isotopes and therefore
creation of atomic weapon and atomic power stations.
Six Nobel prizes were won by Carrer in 1932, Kuhn in 1938, Ruzicka in 1939, Martin and Synge in 1952, Sanger in 1958 and 1980 - authors, whose achievements depended to a significant degree on
use of chromatographic analysis.
In
development of chromatography, a process that goes on up to-day, a definite tendency is traced. After
substantial theoretical and technological "gush" it follows to provide
equipment with additional parts allowing
enlargement of
analytical possibilities of
chromatograph. On this background it is considered in - time
development of Chromabarography - a new basic technology of chromatography.
What does it present itself, what does it give to
user and producer of
equipment? After all,
heart of chromatography is
chromatographic column. The theory of gas chromatography, presented by
equation of Van Deemter H = A + B/u + Cu shows that for each chromatographic separation there exists an optimal flow rate above and below which
column efficiency is reduced.
In practice,
linear speed of
sample zone moved by
carrier gas, is changed continuously and increases as it approaches
outlet, which results in a non-effective use of a part of
column.
Yet
linear speed may be kept constant by programming
movement of
pressure gradient along
column, realizing
function pressure - location - time and keeping ∆ p constant at
ends of
chromatographic column during
whole process of analysis.
For
first time in
world this basic technology was worked out and proposed by me, based on
investigation of
factors of diffusion and kinetics, and includes
meaning "bar-gradient chromatography" or Chromabarography. For its realization an equipment was invented and defended by a Russia patent. As a result a maximum possible efficiency (Hayrapetyan's Effect) of column is obtained at a minimum length, which at
same time is optimal as well, as in difference to
ordinary column further increase in column length increases
analyses time. However these are not
only advantages of Chromabarography. On
contrary, new interesting possibilities of its modifications are opened which foresee: of combined application of
moving gradients of pressure and temperature (Chromabarothermography)
or of
moving of pressure gradient along
column simultaneously with temperature programming affected equally on all
separation column (Chromabarograph with temperature programming). Amongst other advantages of scientific value may be mentioned: The possibility of bar-focusing on each component to solve complex analytical problems on a singular gas chromatographic column, in difference to two or multistage columns.