Endometriosis and ConceptionEndometriosis is a common, yet poorly understood disease. It can strike women of any socioeconomic class, age, or race. It is estimated that between 10 and 20 percent of American women of childbearing age have endometriosis.
While some women with endometriosis may have severe pelvic pain, others who have
condition have no symptoms. Nothing about endometriosis is simple, and there are no absolute cures. The disease can affect a woman's whole existence--her ability to work, her ability to reproduce, and her relationships with her mate, her child, and everyone around her.
What is Endometriosis?
The name endometriosis comes from
word "endometrium,"
tissue that lines
inside of
uterus. If a woman is not pregnant, this tissue builds up and is shed each month. It is discharged as menstrual flow at
end of each cycle. In endometriosis, tissue that looks and acts like endometrial tissue is found outside
uterus, usually inside
abdominal cavity. Endometrial tissue residing outside
uterus responds to
menstrual cycle in a way that is similar to
way endometrium usually responds in
uterus.
At
end of every cycle, when hormones cause
uterus to shed its endometrial lining, endometrial tissue growing outside
uterus will break apart and bleed. However, unlike menstrual fluid from
uterus, which is discharged from
body during menstruation, blood from
misplaced uterus has no place to go. Tissues surrounding
area of endometriosis may become inflamed or swollen. The inflammation may produce scar tissue around
area of endometriosis. These endometrial tissue sites may develop into what are called "lesions," "implants," "nodules," or "growths."
Endometriosis is most often found in
ovaries, on
fallopian tubes, and
ligaments supporting
uterus, in
internal area between
vagina and rectum, on
outer surface of
uterus, and on
lining of
pelvic cavity. Infrequently, endometrial growths are found on
intestines or in
rectum, on
bladder, vagina cervix, and vulva (external genitals), or in abdominal surgery scars, Very rarely, endometrial growths have been found outside
abdomen, in
thigh, arm, or lung.
Physicians may use stages to describe
severity of endometriosis. Endometrial implants that are small and not widespread are considered minimal or mild endometriosis. Moderate endometriosis means that larger implants or more extensive scar tissue is present. Severe endometriosis is used to describe large implants and extensive scar tissue.
What are
Symptoms?
Most commonly,
symptoms of endometriosis start years after menstrual periods begin. Over
years,
symptoms tend to gradually increase as
endometriosis areas increase in size. After menopause,
abnormal implants shrink away and
symptoms subside. The most common symptom is pain, specially excessive menstrual cramps (dysmenorrhea) which may be felt in
abdomen or lower back or pain during or after sexual activity (dyspareunia). Infertility occurs in about 30-40 percent of women with endometriosis.
Rarely,
irritation caused by endometrial implants may progress into infection or abscesses causing pain independent of
menstrual cycle. Endometrial patches may also be tender to touch or pressure,
intestinal pain may also result from endometrial patches on
walls of
colon or intestine. The amount of pain is not always related to
severity of
disease. Some women with severe endometriosis have no pain; while others with just a few small growths have incapacitating pain.
Endometrial cancer is very rarely associated with endometriosis, occurring in less than 1 percent of women who have
disease. When it does occur, it is usually found in more advanced patches of endometriosis in older women and
long-term outlook in these unusual cases is reasonably good.
How is Endometriosis Related to Fertility Problems?
Severe endometriosis with extensive scarring and organ damage may affect fertility. It is considered one of
three major causes of female infertility. However, unsuspected or mild endometriosis is a common finding among infertile women. How this type of endometriosis affects fertility is still not clear.
While
pregnancy rates for patients with endometriosis remain lower than those of
general population, most patients with endometriosis do not experience fertility problems. We do not have a clear understanding of
cause-effect relationship of endometriosis and infertility