Bextra Withdrawal Could Be Just the Beginning of Trouble for Pfizer

Written by Charles Essmeier


The pharmaceutical industry is a tremendously profitable one, as anyone who readsrepparttar business pages of their newspaper can see. Although it can take years to develop a new drug and bring it to market,repparttar 140247 profits obtained from a breakthrough drug can be staggering. Last year Merck sold about $2.5 billion worth of Vioxx, and Pfizer sold about $1.3 billion worth of Bextra. The profits are huge, but so arerepparttar 140248 losses if a problem should develop with a pharmaceutical product. Pfizer voluntarily withdrewrepparttar 140249 popular anti-inflammatory drug Bextra fromrepparttar 140250 market last month, and their stock has suffered from bothrepparttar 140251 loss of sales andrepparttar 140252 potential for a large number of product liability lawsuits. Pfizer may have to endure a double whammy this year asrepparttar 140253 FDA announced that they are investigating reports thatrepparttar 140254 impotence drug Viagra may be linked to cases of blindness in male users. Cialis and Levitra were also mentioned inrepparttar 140255 report, although most ofrepparttar 140256 cases involvedrepparttar 140257 use of Viagra.

The FDA reports shouldn’t cause alarm;repparttar 140258 agency says that it is investigating fewer than 50 incidents of blindness in patients who use a drug that has been used by more than twenty million people since its introduction seven years ago. The FDA investigation says less aboutrepparttar 140259 likelihood of blindness in patients than it does aboutrepparttar 140260 agency’s own concerns about its reputation. The FDA rightly insists

Should You Douche?

Written by Naweko San-Joyz


The only thing a woman can say for certain about her vagina is that it is drenched in mystery. And with this mystery comes a bounty of myths. One myth marringrepparttar woman’s body isrepparttar 140229 concept that her vagina is a filthy pit. Frequent marketing of feminine douches does nothing to arrest this myth. But isrepparttar 140230 vagina dirty and should a woman douche?

A substantial body of medical evidence makes a clear case that douching is not necessary and in some cases unhealthy.

Researchers fromrepparttar 140231 University of Pittsburgh led by Dr. Roberta Ness discovered that most women are introduced torepparttar 140232 concept of douching by their mothers, sisters, or girlfriends. Yet this well-intentioned sisterly advice has left too many women misinformed about their vaginal health. For instance, a study atrepparttar 140233 University of Alabama at Birmingham asked 729 women why they douched. Twenty-one percent ofrepparttar 140234 participants said that they believed douching killed infectious germs, while 27% believed that douching prevented pregnancy. Neither assumption is true.

As writer Mary Ann Innacchinoe explains in an “American Journal of Nursing” article,repparttar 140235 vagina contains, lactobacilli, "good", aerobic bacteria that cleanserepparttar 140236 vagina and protect it from infection. Lactobacilli release hydrogen peroxide, a natural disinfectant. The presence of hydrogen peroxide helps keep potentially harmful anaerobic bacteria in balance.

Ironically, some women view menstruation as a time whenrepparttar 140237 vagina most needs a douche. After menstruation, vaginal mucus returns to its thicker, characteristically non-fertile state, which makes it more difficult for pathogens to enter and infectrepparttar 140238 vagina. Douching could wash this protective coating away and invite vaginal bacterial imbalances and infections. For example, a 2004 study published inrepparttar 140239 medical journal “Sexually Transmitted Diseases” linked douching after menses with an increased risk of bacterial vaginosis.

Bacterial vaginosis, or an excess of harmful bacteria inrepparttar 140240 vagina, is one ofrepparttar 140241 most common reasons women visit their gynecologist. Symptoms of bacterial vaginosis include a gray or frothy vaginal discharge, a “fishy” odor after intercourse, vaginal itching and a vaginal pH greater than 4.5.

While douching can provoke bacterial vaginosis, it may also encouragerepparttar 140242 herpes virus. In 2003, researchers fromrepparttar 140243 Magee-Womens Research Institute in Pittsburgh, Pennsylvania questioned why women are more susceptible torepparttar 140244 herpes simplex virus type 2 (HSV-2) infection than men. After examining 1207 women aged 18 to 30 from three Pittsburgh health clinics,repparttar 140245 investigators noted that women who douche, smoke, have sex with uncircumcised partners, or have bacterial vaginosis are at greater risk for contracting an HSV-2 infection.

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