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The chair cannot be too comfortable because it will allow
body to slouch easily, creating problems. On
other hand,
office chair cannot be too hard either. While selecting an office chair, you have to focus on these aspects and not just
looks or comfort of
chair.
An entire new science is devoted to
study of human capabilities and health in relation to work demands. This is called ergonomics.
However, even if you have
best-designed ergonomics friendly office chair in
world, it is not a wise idea to keep sitting in it for
whole day! Static activity for a long time is not good for
back.
You must move out of
chair for at least 5 minutes every hour. Move around, walk a little and maybe do some stretching exercises. Your physical fitness will ensure proper protection against back injury.

Nick Telford worked in office environments for more than 30 years. A few years ago he developed back problems, and discovered it was due to bad posture in his chairs. He decided to reaearch office chairs, and find out exactly what is the best way to sit for 8 hours a day or more... now he's written a series of article to help others.