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Environmental and lifestyle factors are known to cause oxidative stress and lower glutathione levels - resulting in birth defects, abortion and miscarriages in pregnancy.
Some of known teratogens (causing birth defects) in pregnancy include:
o Radiation o Pesticides and Persistent Organic Pollutants (POPs) o Air pollution o Heavy metals (mercury, cadmium, arsenic) o Vinyl chloride o Acryonitrile o Excess Oxygen (hyperoxia) o Anti-psychotic and anti-epileptic drugs (AEDs) o Thalidomide o Cigarette smoke o Alcohol (ethanol) consumption
Maternal health factors that increase free radicals and cause birth defects include:
o Diabetes o Pre-eclampsia o Infection and Inflammation
Glutathione and other antioxidants attenuate oxidative stress in pregnant women with inflammation or maternal conditions like diabetes and pre-eclampsia, and in fetuses at risk for developing cystic fibrosis.
Supplementation with glutathione precursors and antioxidants can decrease incidence of birth defects and protect both mothers and fetus from damaging and possibly fatal consequences of pregnancy complications.
Glutathione (GSH ) also prevents or minimizes oxidative stress that occurs during labor and birth process.
Perinatal or birth asphyxia/hypoxia (deprivation of oxygen supply to brain) in preterm deliveries and labor can lead to cerebral palsy, respiratory distress syndrome, irreversible brain injury, and permanent neurological and intellectual handicaps.
Administration of glutathione precursor, N-Acetyl-Cysteine (NAC), to pregnant mother partially prevents oxidative stress during birth process in premature infants.
Currently, American College of Obstetrics and Gynecology advises all pregnant women to take a prenatal vitamin containing antioxidants.
In addition, they advise eating lots of fresh fruits and vegetables, best sources of antioxidant protection.
For a detailed report with references on role of glutathione in pregnancy, visit: http://www.1whey2health.com/glutathione_pregnancy.htm
Priya Shah is the Editor of "The Glutathione Report" For regular updates on the health benefits of glutathione subscribe here http://www.glutathione-report.com For a free report on Glutathione in Health and Disease visit http://www.1whey2health.com