Don't overuse frames Use only a limited number of frames. Always check if screen doesn't get crammed if a low resolution screen is used.

Do vertical align content of table cells You do you use table cells to get your info on right position? Then be sure to align content vertically.

Don't mix horizontal aligning Mixing centered text and text that's left aligned makes a mess of your page. If you want to center text do it consistently. Exceptions are centering text of headers or centered text placed in a border.

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I see many web designers who seem to think nobody is using 800 by 600. Ive done several polls and gathered statistics on resolution and it has hovered around 10% for quite some time. I suspect this is people who have old computers and are not business users. All they accomplish is lost visitors and possible sales.

You can check your website in different resolutions by right clicking your desktop and selecting Properties, then go into settings tab to change your resolution.

I would suggest making sure your website is viewable equally in 800 by 600 and 1024 by 768. This basically covers all screen resoultions.